MATERNAL AND FETAL OUTCOMES ASSOCIATED WITH HYPERTENSIVE DISORDERS OF PREGNANCY: A PROSPECTIVE ANALYSIS

Abstract

It is the long term health outcomes that the international health care system attributes high morbidity and mortality of the mother and the child as a result of hypertensive pregnancy disorders that is gradually becoming common.This was done with a prospective intention of establishing maternal, fetal and postpartum impacts of single phenotypes of hypertensive disorders that involves chronic, gestational, preeclampsia and superimposed preeclampsia.It was proposed as a mixed method research, which was a longitudinal quantitative clinical data and situational qualitative analysis. The analysis of disease progression, maternal cardiovascular burden, neonatal outcomes, and consumption and thematic synthesis of care-related factors applied in healthcare was done through multilevel and state-transition models.The high indices of multivariate severity were linked to severe hypertensive phenotypes, which were linked to high levels of endothelial stress response and increased risks of developing diseases in particular preeclampsia and superimposed preeclampsia. Such circumstances were linked to fluctuating tendency of blood pressure, excessive cardiovascular load during the postpartum care, and significantly increased expenditures on healthcare. Results on fetal outcome were similar to the patterns of maternal risk distribution whereby larger discrepancies of growth parameters, more patterns of higher levels of morbidity among the newborn babies and the maternal-fetal risk correlate of severe morbidity outcomes were found. Examinations at the system level revealed that superimposed preeclampsia had the greatest maternal and neonatal weight.Hypertensive disorders of pregnancy is a dynamic continuum of multi-system disorders on a more disastrous outcome on both the mother and the fetus. The unusual phenotype-related risk stratification, the early diagnosis and the long-term follow-up of the post-partum are required that would lead to the improved prognosis and decreased cardiovascular risks in the long-term.